The name Fonseca has its own particular significance in Salamanca.The Camino Fonseca is the Jacobean pathway which links Salamanca to Santiago de Compostela, along the Vía de la Plata as far as the Granja de Moreruela, where it joins up with the Camino Sanabrés which leads to Galicia. Fonseca is also the name of the Colegio (College) built by Diego de Silóe and the Palacio (Palace) built by Rodrigo Gil de Hontañón.

Today, this symbol of artistic distinction is also the home of the abba Fonseca Hotel, which, for the last three years, has shared this historic and artistic site with monuments such as the Casa de las Conchas, the Plaza Mayor, the Cathedral, the Campo de San Francisco, the Casa Lis museum and the University Hospital, all just a few metres away.

The city's economic life revolves around the services sector, as it is an important touristic centre. The other driving force remains the University, as well as agriculture and livestock.